Etrych, T: search on Z-Library

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1

Synthesis of HPMA Copolymers Containing Doxorubicin Bound via a Hydrazone Linkage. Effect of Spacer on Drug Release and in vitro Cytotoxicity

Tomáš Etrych, Petr Chytil, Markéta Jelínková, Blanka Říhová, Karel Ulbrich

Journal:

Macromolecular Bioscience

Year:

2002

Language:

english

File:

PDF, 266 KB

english, 2002

2

Synergistic effect of HPMA copolymer-bound doxorubicin and dexamethasone in vivo on mouse lymphomas

Kostkova, H., Etrych, T., Rihova, B., Ulbrich, K.

Journal:

Journal of Bioactive and Compatible Polymers

Year:

2011

Language:

english

File:

PDF, 326 KB

english, 2011

3

Thermoresponsive Polymer Micelles as Potential Nanosized Cancerostatics

Laga, Richard, Janoušková, Olga, Ulbrich, Karel, Pola, Robert, Blažková, Jana, Filippov, Sergey K., Etrych, Tomáš, Pechar, Michal

Journal:

Biomacromolecules

Year:

2015

Language:

english

File:

PDF, 2.50 MB

english, 2015

4

PCL-PEG graft copolymers with tunable amphiphilicity as efficient drug delivery systems

Al Samad, Assala, Bethry, Audrey, Koziolová, Eva, Netopilik, Milos, Etrych, Tomáš, Bakkour, Youssef, Coudane, Jean, El Omar, Fawaz, Nottelet, Benjamin

Journal:

Journal of Materials Chemistry B

Year:

2016

Language:

english

File:

PDF, 1.22 MB

english, 2016

5

Overcoming multidrug resistance using folate receptor-targeted and pH-responsive polymeric nanogels containing covalently entrapped doxorubicin

Chen, Y., Tezcan, O., Li, D., Beztsinna, N., Lou, B., Etrych, T., Ulbrich, K., Metselaar, J. M., Lammers, T., Hennink, W. E.

Journal:

Year:

2017

Language:

english

File:

PDF, 4.50 MB

english, 2017

6

Coating Persistent Luminescence Nanoparticles With Hydrophilic Polymers for in vivo Imaging

Liu, Jianhua, KotrchovÃ¡, Lenka, LÃ©cuyer, Thomas, Corvis, Yohann, Seguin, Johanne, Mignet, Nathalie, Etrych, TomÃ¡Å¡, Scherman, Daniel, RandÃ¡rovÃ¡, Eva, Richard, Cyrille

Journal:

Frontiers in Chemistry

Year:

2020

File:

PDF, 1.84 MB

2020

7

Hydroxybisphosphonate-containing polymeric drug-delivery systems designed for targeting into bone tissue

Martin Hrubý, Tomáš Etrych, Jan Kučka, Michaela Forsterová, Karel Ulbrich

Journal:

Journal of Applied Polymer Science

Year:

2006

Language:

english

File:

PDF, 281 KB

english, 2006

8

N-(2-hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin. I. New synthesis, physicochemical characterization and preliminary biological evaluation

Tomáš Etrych, Tomáš Mrkvan, Petr Chytil, Čestmír Koňák, Blanka Říhová, Karel Ulbrich

Journal:

Journal of Applied Polymer Science

Year:

2008

Language:

english

File:

PDF, 162 KB

english, 2008

9

Polymer-coated polyethylenimine/DNA complexes designed for triggered activation by intracellular reduction

Robert C. Carlisle, Tomas Etrych, Simon S. Briggs, Jon A. Preece, Karel Ulbrich, Leonard W. Seymour

Journal:

The Journal of Gene Medicine

Year:

2004

Language:

english

File:

PDF, 136 KB

english, 2004

10

Polymeric anticancer drugs with pH-controlled activation

K Ulbrich, T Etrych, P Chytil, M Pechar, M Jelinkova, B Rihova

Journal:

International Journal of Pharmaceutics

Year:

2004

Language:

english

File:

PDF, 171 KB

english, 2004

11

Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin

Marina Talelli, Maryam Iman, Amir K. Varkouhi, Cristianne J.F. Rijcken, Raymond M. Schiffelers, Tomas Etrych, Karel Ulbrich, Cornelus F. van Nostrum, Twan Lammers, Gert Storm, Wim E. Hennink

Journal:

Year:

2010

Language:

english

File:

PDF, 486 KB

english, 2010

12

Preclinical Evaluation of Linear HPMA-Doxorubicin Conjugates with pH-Sensitive Drug Release: Efficacy, Safety, and Immunomodulating Activity in Murine Model

Milada Sirova, Tomas Mrkvan, Tomas Etrych, Petr Chytil, Pavel Rossmann, Marketa Ibrahimova, Lubomir Kovar, Karel Ulbrich, Blanka Rihova

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 437 KB

english, 2010

13

Doxorubicin attached to HPMA copolymer via amide bond modifies the glycosylation pattern of EL4 cells

Lubomir Kovar, Tomas Etrych, Martina Kabesova, Vladimir Subr, David Vetvicka, Ondrej Hovorka, Jiri Strohalm, Jan Sklenar, Petr Chytil, Karel Ulbrich, Blanka Rihova

Journal:

Year:

2010

Language:

english

File:

PDF, 430 KB

english, 2010

14

Use of synthetic vectors for neutralising antibody resistant delivery of replicating adenovirus DNA

Carlisle, R C, Briggs, S S, Hale, A B, Green, N K, Fisher, K D, Etrych, T, Ulbrich, K, Mautner, V, Seymour, L W

Journal:

Year:

2006

Language:

english

File:

PDF, 144 KB

english, 2006

15

High-molecular-weight Polymers Containing Biodegradable Disulfide Bonds: Synthesis and In Vitro Verification of Intracellular Degradation

Etrych, T., Kovar, L., Subr, V., Braunova, A., Pechar, M., Chytil, P., Rihova, B., Ulbrich, K.

Journal:

Journal of Bioactive and Compatible Polymers

Year:

2010

Language:

english

File:

PDF, 437 KB

english, 2010

16

HPMA Copolymer Conjugates of Paclitaxel and Docetaxel with pH-Controlled Drug Release

Etrych, Tomáš, Šírová, Milada, Starovoytova, L., Říhová, Blanka, Ulbrich, Karel

Journal:

Molecular Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 584 KB

english, 2010

17

New HPMA copolymer-based drug carriers with covalently bound hydrophobic substituents for solid tumour targeting

P. Chytil, T. Etrych, Č. Koňák, M. Šírová, T. Mrkvan, J. Bouček, B. Říhová, K. Ulbrich

Journal:

Journal of Controlled Release

Year:

2008

Language:

english

File:

PDF, 423 KB

english, 2008

18

Hydrolytically Degradable Polymer Micelles for Anticancer Drug Delivery to Solid Tumors

Petr Chytil, Tomáš Etrych, Libor Kostka, Karel Ulbrich

Journal:

Macromolecular Chemistry and Physics

Year:

2012

Language:

english

File:

PDF, 545 KB

english, 2012

19

Polyelectrolyte complex formation and stability when mixing polyanions and polycations in salted media: A model study related to the case of body fluids

Tomáš Etrych, Laurent Leclercq, Mahfoud Boustta, Michel Vert

Journal:

European Journal of Pharmaceutical Sciences

Year:

2005

Language:

english

File:

PDF, 168 KB

english, 2005

20

HPMA-based polymer conjugates with drug combination

Hana Krakovičová, Tomáš Etrych, Karel Ulbrich

Journal:

European Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 531 KB

english, 2009

21

N-(2-Hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation

Petr Chytil, Tomáš Etrych, Jaroslav Kříž, Vladimír Šubr, Karel Ulbrich

Journal:

European Journal of Pharmaceutical Sciences

Year:

2010

Language:

english

File:

PDF, 521 KB

english, 2010

22

Biodegradable star HPMA polymer conjugates of doxorubicin for passive tumor targeting

Tomáš Etrych, Jiří Strohalm, Petr Chytil, Peter Černoch, Larisa Starovoytova, Michal Pechar, Karel Ulbrich

Journal:

European Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 592 KB

english, 2011

23

Overcoming cellular multidrug resistance using classical nanomedicine formulations

Sijumon Kunjachan, Andrzej Błauż, Diana Möckel, Benjamin Theek, Fabian Kiessling, Tomas Etrych, Karel Ulbrich, Louis van Bloois, Gert Storm, Grzegorz Bartosz, Błażej Rychlik, Twan Lammers

Journal:

European Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 725 KB

english, 2012

24

HPMA copolymers containing doxorubicin bound by a proteolytically or hydrolytically cleavable bond: comparison of biological properties in vitro

M. Kovář, L. Kovář, V. Šubr, T. Etrych, K. Ulbrich, T. Mrkvan, J. Loucká, B. Říhová

Journal:

Journal of Controlled Release

Year:

2004

Language:

english

File:

PDF, 376 KB

english, 2004

25

Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers

Twan Lammers, Rainer Kühnlein, Maria Kissel, Vladimir Subr, Tomas Etrych, Robert Pola, Michal Pechar, Karel Ulbrich, Gert Storm, Peter Huber, Peter Peschke

Journal:

Journal of Controlled Release

Year:

2005

Language:

english

File:

PDF, 373 KB

english, 2005

26

Chemotherapy based on HPMA copolymer conjugates with pH-controlled release of doxorubicin triggers anti-tumor immunity

Tomas Mrkvan, Milada Sirova, Tomas Etrych, Petr Chytil, Jiri Strohalm, Dana Plocova, Karel Ulbrich, Blanka Rihova

Journal:

Journal of Controlled Release

Year:

2005

Language:

english

File:

PDF, 154 KB

english, 2005

27

Properties of HPMA copolymer–doxorubicin conjugates with pH-controlled activation: Effect of polymer chain modification

Petr Chytil, Tomáš Etrych, Čestmír Koňák, Milada Šírová, Tomáš Mrkvan, Blanka Říhová, Karel Ulbrich

Journal:

Journal of Controlled Release

Year:

2006

Language:

english

File:

PDF, 263 KB

english, 2006

28

Star-shaped immunoglobulin-containing HPMA-based conjugates with doxorubicin for cancer therapy

Tomáš Etrych, Tomáš Mrkvan, Blanka Říhová, Karel Ulbrich

Journal:

Journal of Controlled Release

Year:

2007

Language:

english

File:

PDF, 381 KB

english, 2007

29

Doxorubicin release is not a prerequisite for the in vitro cytotoxicity of HPMA-based pharmaceuticals: In vitro effect of extra drug-free GlyPheLeuGly sequences

B. Říhová, J. Strohalm, O. Hovorka, V. Šubr, T. Etrych, P. Chytil, R. Pola, D. Plocová, J. Bouček, K. Ulbrich

Journal:

Journal of Controlled Release

Year:

2008

Language:

english

File:

PDF, 321 KB

english, 2008

30

Conjugates of doxorubicin with graft HPMA copolymers for passive tumor targeting

Tomáš Etrych, Petr Chytil, Tomáš Mrkvan, Milada Šírová, Blanka Říhová, Karel Ulbrich

Journal:

Journal of Controlled Release

Year:

2008

Language:

english

File:

PDF, 498 KB

english, 2008

31

Biodegradable high-molecular-weight polymer drug carriers based on HPMA copolymers

P. Chytil, T. Etrych, K. Ulbrich

Journal:

Journal of Controlled Release

Year:

2008

Language:

english

File:

PDF, 113 KB

english, 2008

32

HPMA copolymer conjugates for dual therapy

T. Etrych, H. Krakovičová, M. Šírová, B. Říhová, K. Ulbrich

Journal:

Journal of Controlled Release

Year:

2008

Language:

english

File:

PDF, 183 KB

english, 2008

33

HPMA copolymer conjugates with reduced anti-CD20 antibody for cell-specific drug targeting. I. Synthesis and in vitro evaluation of binding efficacy and cytostatic activity

Tomáš Etrych, Jiří Strohalm, Lubomír Kovář, Martina Kabešová, Blanka Říhová, Karel Ulbrich

Journal:

Journal of Controlled Release

Year:

2009

Language:

english

File:

PDF, 598 KB

english, 2009

34

Biodegradable star HPMA polymer–drug conjugates: Biodegradability, distribution and anti-tumor efficacy

Tomáš Etrych, Lubomír Kovář, Jiří Strohalm, Petr Chytil, Blanka Říhová, Karel Ulbrich

Journal:

Journal of Controlled Release

Year:

2011

Language:

english

File:

PDF, 822 KB

english, 2011

35

New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties

Tomáš Etrych, Markéta Jelı́nková, Blanka Řı́hová, Karel Ulbrich

Journal:

Journal of Controlled Release

Year:

2001

Language:

english

File:

PDF, 335 KB

english, 2001

36

Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes

B. R̆ı́hová, T. Etrych, M. Pechar, M. Jelı́nková, M. Štastný, O. Hovorka, M. Kovář, K. Ulbrich

Journal:

Journal of Controlled Release

Year:

2001

Language:

english

File:

PDF, 89 KB

english, 2001

37

Differences in the intracellular fate of free and polymer-bound doxorubicin

Ondřej Hovorka, M Št’astný, T Etrych, V Šubr, J Strohalm, K Ulbrich, B Řı́hová

Journal:

Journal of Controlled Release

Year:

2002

Language:

english

File:

PDF, 1.32 MB

english, 2002

38

HPMA-hydrogels containing cytostatic drugs: Kinetics of the drug release and in vivo efficacy

Marek Št’astný, Dana Plocová, Tomáš Etrych, Marek Kovář, Karel Ulbrich, Blanka Řı́hová

Journal:

Journal of Controlled Release

Year:

2002

Language:

english

File:

PDF, 489 KB

english, 2002

39

HPMA copolymers with pH-controlled release of doxorubicin: In vitro cytotoxicity and in vivo antitumor activity

K Ulbrich, T Etrych, P Chytil, M Jelı́nková, B Řı́hová

Journal:

Journal of Controlled Release

Year:

2003

Language:

english

File:

PDF, 805 KB

english, 2003

40

Cytostatic and immunomobilizing activities of polymer-bound drugs: experimental and first clinical data

Blanka Řı́hová, Jiřı́ Strohalm, Jana Prausová, Katerina Kubáčková, Markéta Jelı́nková, Lad’ka Rozprimová, Milada Šı́rová, Dana Plocová, Tomáš Etrych, Vladimı́r Šubr, Tomáš Mrkvan, Marek Kovář, Karel U

Journal:

Journal of Controlled Release

Year:

2003

Language:

english

File:

PDF, 331 KB

english, 2003

41

HPMA copolymer-bound doxorubicin targeted to tumor-specific antigen of BCL1 mouse B cell leukemia

M Kovář, T Mrkvan, J Strohalm, T Etrych, K Ulbrich, M Štastný, B Řı́hová

Journal:

Journal of Controlled Release

Year:

2003

Language:

english

File:

PDF, 622 KB

english, 2003

42

Self-assembly of biodegradable copolyester and reactive HPMA-based polymers into nanoparticles as an alternative stealth drug delivery system

Jäger, Eliézer, Jäger, Alessandro, Etrych, Tomáš, Giacomelli, Fernando Carlos, Chytil, Petr, Jigounov, Alexander, Putaux, Jean-Luc, Říhová, Blanka, Ulbrich, Karel, Štěpánek, Petr

Journal:

Year:

2012

Language:

english

File:

PDF, 655 KB

english, 2012

43

Noninvasive Optical Imaging of Nanomedicine Biodistribution

Kunjachan, Sijumon, Gremse, Felix, Theek, Benjamin, Koczera, Patrick, Pola, Robert, Pechar, Michal, Etrych, Tomas, Ulbrich, Karel, Storm, Gert, Kiessling, Fabian, Lammers, Twan

Journal:

Year:

2013

Language:

english

File:

PDF, 797 KB

english, 2013

44

Characterisation of the binding interaction between poly(L-lysine) and DNA using the fluorescamine assay in the preparation of non-viral gene delivery vectors

Martin L. Read, Thomas Etrych, Karel Ulbrich, Leonard W. Seymour

Journal:

Year:

1999

Language:

english

File:

PDF, 167 KB

english, 1999

45

Induction and activation of meiosis and subsequent parthenogenetic development of growing pig oocytes using calcium ionophore A23187

Markéta Sedmı́ková, Jana Burdová, Jaroslav Petr, Milan Etrych, Jiřı́ Rozinek, František Jı́lek

Journal:

Year:

2003

Language:

english

File:

PDF, 119 KB

english, 2003

46

HPMA-hydrogels result in prolonged delivery of anticancer drugs and are a promising tool for the treatment of sensitive and multidrug resistant leukaemia

M Št'astný, D Plocová, T Etrych, K Ulbrich, B Řı́hová

Journal:

European Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 160 KB

english, 2002

47

Polymer Carriers for Anticancer Drugs Targeted to EGF Receptor

Studenovsky, Martin, Pola, Robert, Pechar, Michal, Etrych, Tomas, Ulbrich, Karel, Kovar, Lubomir, Kabesova, Martina, Rihova, Blanka

Journal:

Macromolecular Bioscience

Year:

2012

Language:

english

File:

PDF, 312 KB

english, 2012

48

Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy

Marina Talelli, Sabrina Oliveira, Cristianne J.F. Rijcken, Ebel H.E. Pieters, Tomas Etrych, Karel Ulbrich, Rene C.F. van Nostrum, Gert Storm, Wim E. Hennink, Twan Lammers

Journal:

Year:

2013

Language:

english

File:

PDF, 683 KB

english, 2013

49

HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity

Etrych, Tomáš, Šubr, Vladimír, Strohalm, Jiří, Šírová, Milada, Říhová, Blanka, Ulbrich, Karel

Journal:

Journal of Controlled Release

Year:

2012

Language:

english

File:

PDF, 793 KB

english, 2012

50

Combination chemotherapy using core-shell nanoparticles through the self-assembly of HPMA-based copolymers and degradable polyester

Jäger, Eliézer, Jäger, Alessandro, Chytil, Petr, Etrych, Tomáš, Říhová, Blanka, Giacomelli, Fernando Carlos, Štěpánek, Petr, Ulbrich, Karel

Journal:

Journal of Controlled Release

Year:

2013

Language:

english

File:

PDF, 971 KB

english, 2013